Au@Ag@Pt core–shell nanorods regulating Ag release behavior endow titanium antibacterial activity and biocompatibility

Although titanium and its alloys are extensively used in orthopedics dentistry fields, implant failures still happen because of implant-associated infections. Herein, Au@Ag@Pt core–shell nanorods with noble metal combination were fabricated assembled on medical surface the antibacterial activity biocompatibility investigated. The results showed that rates Ti–Au@Ag@Pt against S. epidermidis P. aeruginosa 89.7% 92.7%, respectively. Besides, no obvious cell toxicity MC3T3-E1 cells grew well sample surface. It was discovered Pt shell layer slowed down Ag ion release rate which endowed both good biocompatibility.